抄録
In this paper four cases of oral malignant tumor occurred in children were reported, at the Department of Dentistry and Oral Surgery, Keio University Hospital from 1984 to 2004. They were malignant lymphoma of the lower lip, squamous cell carcinoma of the lower gum, neuroblastoma of the mandible, and osteosarcoma of the mandible.
[Case 1] A 12 year old-girl came to our hospital with a chief complaint of a painless tumor of lower lip. The tumor was surgically removed under general anesthesia, and a pathological diagnosis of malignant lymphoma was made. After the operation, radiation therapy (40Gy) was given. There is no evidence of recurrence about 17 years and 1 month after the operation.
[Case 2] A 12 year old-boy was referred to our hospital because he was pointed out to have an ulcer of lower gum at the dental check-up of his school. The pathological diagnosis by the biopsy was squamous cell carcinoma.
[Case 3] The patient was a 14 year old-boy with a chief complaint of gingival swelling in the left molar region of the mandible. The pathological diagnosis of the mandibular lesion by biopsy was neuroblastoma, and the primary tumor was found in the left adrenal gland. Chemotherapy, surgical resection and radiation were given. Twelve years and 4 months after the mandiblectomy, the patient is alive with no evidence of local recurrence or metastasis.
[Case 4] A 9 year old-girl complained of a painless swelling in the chin. Pre-and post-operative chemotherapy (MTX+VCR) was administered, mandiblectomy combined with neck dissection was performed. However 10 months later, there was a metastasis of the lung. She died 2 years and 4 months after the first medical examination.
