Abstract
Microvascular damage is closely related to tlle pathogenesis of systemic sclerosis(SSc)or juvenile
dermatomyositis(JDM). Nailfold Video Capillaroscopy(NVC)is a convenient and noninvasive method to
analyze the capillary morphology and architecture. Abnormal NVC findings including giant capillaries are
specifically observed in patients with SSc and JDM. Early in the disease, thesc findings can be well recognized by
NVC,which is reported to have both diagnostic and prognostic values in SSc and JDM. In this report, we report
sequential NVC findings in one patient with SSc and two patients with JDM.NVC patterns were correlated with
disease activity of these diseases. NVC is the convenient and safe method to analyze microvascular abnormalities
and is useful for differential diagnosis and evaluation of disease activity in SSc and JDM.