RESORBABLE POLYMER COATINGS FOR HIGHLY POROUS PHOSPHATE GLASSES

抄録

Resorbable scaffolds for bone tissue engineering were fabricated from open-pore phosphate glasses coated with a thin, degradable polymer coating. This coating, consisting in a three-dimensional polymer network, was prepared by radical polymerization of a novel oligolactide macromer. It was demonstrated that the inter-connective pore structure of the phosphate glasses is preserved in the coated samples. The mechanical stability, especially the compression strength, of the scaffolds and their processibility could be significantly improved by the developed polymer coating.