Study on low-speed cell manipulation in micro-channels

Abstract

When red blood cells pass through a blood vessel, the cells are subject to physical stress as they pass through the tube. In addition, since there is a strong correlation between diseases and the deformability of cells, we would like to focus on the behavior of cells as they pass through the tube while under load. Therefore, in this study, we fabricated a micro-channel that corresponds to a capillary and designed a system that reproduces the phenomenon in which cells flow at low speed within the channel. This time, we will discuss the experimental system and problems of micro-channels and low-speed manipulation.