Abstract
It has been often found that the provisionized Japanese monkeys bore limb-malformed babies since 1955 in Japan. We reported that some organochlorin pesticide residues might have related to the cause of the malformation of limbs. It was found that the tissues of the dead Japanese monkeys were contaminated with Heptachlor epoxide, Dieldrin, BHC, DDT, and Chlordane isomers. The concentrations of Heptachlor epoxide in the malformed monkeys were significantly higher (kidney, p<0.05) than those in the normal monkeys. The levels of Heptachlor epoxide (kidney) and Dieldrin (liver) in the adult female monkeys who had borne malformed babies were also significantly higher (p<0.05) than those in the adult females who had not.