抄録
Objective: Free-radicals have been implicated in aging, mutagenesis, inflammation, and other pathological conditions. We conducted a study to clarify the relation between psychological eustress of pleasant feeling and free radical-scavenging cappacity (FRSC) in saliva. Methods: Saliva was collected from 27 healthy volunteers. FRSC before, during, and after watching a cheerful comical video for 30 minutes were measured by using 1,1-diphenyl-2-picrylhydrazyl. Results: The median values of FRSC (μmol/ml) before, at 10, 20 min during, after watching the video were 54.5, 66.8, 66.6, and 69.4, respectively. FRSC values obtained after watching the video were significantly higher than those before watching it (p<0.001). When the FRSC before watching was taken as 1, the value for the group that felt Very good, Good, or Ordinary + Dull while watching the video for 30 min was 1.38, 1.20 or 0.98, respectively (p<0.01). Conclusion: Watching a comical video enhanced the FRSC in saliva; and, in addition, a pleasant feeling boosted it even more. [Jpn J Physiol 54 Suppl:S204 (2004)]
