PSYCHOLOGIA
Online ISSN : 1347-5916
Print ISSN : 0033-2852
ISSN-L : 0033-2852
SPECIAL ISSUE: CONSTITUENTS OF HAPPINESS
Guest Editor: Kazuo Fujita
THE INTERPLAY OF GENETIC AND ENVIRONMENTAL INFLUENCES ON PREFRONTAL FUNCTION AND SELF-REGULATION OF IMPULSIVITY
Michio NOMURA
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ジャーナル フリー

2011 年 54 巻 4 号 p. 241-251

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Self-regulation of impulsivity via maturation of the executive resources benefits our well-being. The review of behavioral, neuroimaging, and pharmacological studies appears to provide evidence of a relationship between the self-regulation of impulsivity, activity of the prefrontal cortex, and serotonergic neurotransmission. Although a wide range of genetic, developmental, and social factors exists, much of this information, their interactive mechanisms in particular, remains to be clarified. Thus, in the present article, I first review the brain functions that underlie self-regulative processes and then provide an update on recent findings regarding serotonergic neurotransmission. Next, by integrating findings from behavioral genetics that examine the association between gene polymorphism and impulsivity, I discuss the bright sides of the risk allele of gene polymorphism. Finally, I argue the future direction of genetic and environmental bidirectional studies.
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© 2011 by the PSYCHOLOGIA SOCIETY
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