8.2.3　炭素線治療における生物学的効果比

高橋 昭久; 吉田 由香里; 安藤 興一

doi:10.3769/radioisotopes.68.701

Section 8 [Radiation Biology] Contribution of HIMAC for Radiation Biology

8.2.3　Relative Biological Effectiveness in Carbon-Ion Therapy

Akihisa Takahashi , Yukari Yoshida, Koichi Ando

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Keywords: HIMAC (Heavy Ion Medical Accelerator in Chiba), linear energy transfer (LET), relative biological effectiveness (RBE)

JOURNAL OPEN ACCESS

2019 Volume 68 Issue 10 Pages 701-707

DOI https://doi.org/10.3769/radioisotopes.68.701

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Abstract

We introduce the results about the relative biological effectiveness (RBE) using HIMAC. Carbon-ion therapy is rated higher concerning the quality of life (QOL) than photon therapy because it has a strong cancer control ability and is considered to be a low-invasive method. It is important to evaluate the dose and to know the relations of linear energy transfer (LET) and RBE for understanding a useful effect of carbon-ion therapy. In this review, we summarize the current status and the meaning of the RBE concept in carbon-ion therapy and highlight outstanding issues.

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