Studies on the Quality and Test Method of Radiopharmaceuticals. (I) Paper Chromatography of Preparations labeled with ¹³¹Iand ¹²⁵I

Abstract

Ordinary paper chromatographic methods for the purity test were studied on some kinds of radiopharmaceuticals labeled with ¹³¹I and ¹²⁵I, using various kinds of developing solvents.
Among these solvents tested, the followings were regarded as the most suitable for purity test;
for sodium radio-iodide: ethanol: water: benzene (65: 35: 1) and methanol: water (75: 25), for radioactive triiodothyronine: n-butanol: dioxane (4: 1) saturated with 2N-ammonium carbonate, for radioactive sodium o-iodolaippurate: n-butanol: ethanol (4: 1) saturated with 2N-ammonium carbonate.