Abstract
We have tested the TSH radioimmunoassay kit (Daiichi Radioisotope Labs., Ltd.) for its basic and clinical determinations. The results of serum TSH in various clinical states and TRH tests were also reported. The sensitivity, reproducibility and recovery of the assay were satisfactory. In normal subjects, serum TSH showed 5.6μU/ml in average, hyperthyroid subjects showed low, and primary hypothyroid subjects showed high levels. With TRH tests, hyperthyroidism showed low or non response, whereas primary hypothyroidism showed exaggerated and delayed response. In secondary hypothyroidism, increase or no increase of serum TSH were observed. In observed values, there was a good correlation with the values obtained by the use of NIH kits.