Abstract
Usefullness of Triosorb M test, measuring thyroid function indirectly, was evaluated in 82 subjects with or without thyroid abnormalities and pregnant women.
A satisfactory reproducibility was obtained in intraassay and interassay; C. V. were ±1.71% and ±2.44% respectively. Triosorb M values were affected by the changes of incubation time and temperature, especially by the latter. Triosorb M values dropped significantly of hyperthyroid sera as incubation temperature rose, while values rose slightly of hypothyroid sera. Incubation time had almost the same effects on hyper-and hypothyroid sera values. A good correlation was observed between Triosorb M values and Triosorb values, incubated at 20°C or 25°C for 20 min. Incubated at 25°C, Triosorb M values were lower than those of Triosorb test of the same hyperthyroid sera. Incubated at 20°C, both tests showed very similar values each other of hyperthyroid sera as well as hypothyoid and normal sera.
In normal subjects, Triosorb M values were 27.9±2.3% with rare overlap with those of hyperthyroid and moderate overlap with those of hypothyroid.
Triosorb M test requires only 0.5 ml of serum and can be carried on in a short time with strict controlling the incubation temperature and time, and might be one of the usefull examinations of thyroid function.
