Clinical Evaluation of Brain Positron Emission Tomography with Inhalation of ¹⁵O Labeled Gas Synthesized by Automated Production System ARIS G1

Abstract

In order to investigate the clinical usefulness of positron emission tomography (PET) studies using the inhalation of oxygen-15 labeled gas, clinical trial was performed. PET studies were carried out using ¹⁵O labeled gas produced by automated ¹⁵O gas production system (ARIS G1) in 72 patients with various neurological disorders. In all cases, the labeled gas was produced in a stable condition by ARIS G1 and no adverse reaction was observed. Overall assessment for the clinical usefulness of PET study using ARIS G1 was determined as follows: 50% as highly useful, 41.7% as useful and 8.3% as fairly useful.
In conclusion, PET studies using ¹⁵O gas production system were useful in patients with various brain diseases.