1992 Volume 41 Issue 2 Pages 71-78
The radio-decomposed rate of acrinol as a model of pharmaceutical component in some different dosages, which were single component as dry powder, double components as aqueous solution and triple components as mixed state in dry or wet fillers, have been investigated in dose range of -300 kGy.
As results, in the cases of single components, the decomposed rate was approximated with linear equation to dose. The other cases such as hydrous dosages, e.g. aqueous solution or mixed in wet fillers, the exponential correlations existed. However, in either case, the residual rate of acrinol after γ-irradiation can be calculated by substitution of three kinds G-values for direct and indirect actions of γ-ray, which are actual values Gs=1.25, Gw=0.80 and Gc=0.145.
