Abstract
Accumulation of 99mTc-MIBI has been reported in several various carcinomas. In this study, 99mTc-MIBI scintigraphy was evaluated to detect recurrent or metastatic lesion in seven patients with thyroid carcinoma. The results were compared with those of 131I scintigraphy and 201T1 scintigraphy.
Bone metastasis and lymphnode metastasis were well demonstrated in 99mTc-MIBI scintigraphy, but 131I scintigraphy allows the best visualization of pulmonary metastasis.
99mTc-MIBI scintigraphy has desirable characteristics including the potential for no thyroid hormone withdrawal, immediate imaging postinjection, and low radiation burden.
In conclusion, it is shown that 99mTc-MIBI scintigraphy is a useful procedure in follow-up of thyroid carcinoma and has the potential for visualization of metastasis when 131I was negative.