Multiple Organ Failure Assessment Can Predict Achievement of Early Postoperative Rehabilitation Goal in Patients Undergoing Type A Acute Aortic Dissection Repair

Abstract

Purpose: The purpose of this study was to investigate whether multiple organ failure assessment measured after surgery predicted the achievement of early postoperative rehabilitation goal in patients undergoing type A acute aortic dissection (AAAD) repair.
Methods: We enrolled 180 AAAD patients (mean age of 65 ± 12 years, 92 males) who had undergone surgery. The sequential organ failure assessment (SOFA) score was used after surgery to measure the degree of multiple organ failure. For the postoperative duration, we investigated the number of days it took patients to successfully complete a 100-meter walk without assistance. The achievement of the early postoperative goal was defined as <15 days. Significant factors that affected achievement of the early postoperative rehabilitation goal were extracted. Cut-off values were determined by using multivariate logistic regression analysis and receiver operating characteristic curves.
Results: Of 180 AAAD patients, 74 did not achieve the early postoperative rehabilitation goal. The SOFA score at 1, 2 and 3 days after surgery were significantly higher in non-achieved patients than achieved patients (p ＜0.01 for all). The SOFA score for the first day after surgery was a significant predictor of achievement of early the postoperative rehabilitation goal (OR, 2.01; 95 % CI, 1.32–3.06; p<0.001). The SOFA score cut-off value was determined to be 6.5, with a sensitivity of 0.84 and a specificity of 0.71.
Conclusions: The SOFA score at first day after surgery is an independent predictor of achievement of early postoperative rehabilitation goal in patients undergoing AAAD repair, with a cut-off value of 6.5.