Article ID: 11305
Objective: The purpose of this study was to clarify the relationship between the acute response of interleukin-6 (IL-6) during exercise and glucose fluctuations/skeletal muscle index (SMI) in patients with abnormal glucose metabolism after acute treatment of coronary artery disease.
Method: A total of 13 patients with abnormal glucose metabolism after acute treatment of coronary artery disease were selected. IL-6 and blood glucose (BG) levels were measured before and immediately after aerobic exercise. SMI was measured using the multi-frequency impedance method to examine the relationship among the amount of change of IL-6 (⊿IL-6), amount of change of BG (⊿BG), and SMI at before and after exercise.
Result: A significant negative correlation between ⊿IL-6 and ⊿BG and a significant positive correlation between ⊿IL-6 and SMI were confirmed (p<0.05).
Conclusion: The result suggested that increased secretion of IL-6 was involved in the promotion of glucose intake into skeletal muscles and the muscle mass was associated with the amount of secreted IL-6 even after one cycle of aerobic exercise.
