Abstract
The purpose of this study was to examine the effect of endurance training by eccentric contraction on mouse quadriceps femoris muscles. Male ICR mice were divided into control (CONT), uphill running (concentrical contraction, +16°, UR), level running (0°, LR) and downhill running (eccentrical contraction, -16°, DR) groups. Running for animals was started at 15 m/min for 20 min, and then the duration of the running was lengthened by 10 min/week. Running was performed 6 days/week for 5 weeks. After 5 weeks running, the quadriceps femoris were removed and glycolytic and oxidative enzymes were measured. Glycolytic enzyme in UR and LR was higher than in CONT, but in DR was not. Oxidative enzyme in UR, LR and DR was higher than in CONT. In conclusion, endurance training by eccentric contraction was not effective for increasing anaerobic metabolism, but was effective for increasing aerobic metabolism.
