Abstract
The purpose of this report is to clarify the clinical pathology and prognosis of postoperative hyperbilirubinemia and to make some strategies. Thirteen patients who experienced total bilirubin of 5.0 mg/dl and over after operation in a recent 2-year period were subjected. Obstructive jaundice was excluded. The mortality rate was so high (54%, 7/13). There were no significant differences in age, blood loss and operating time between survived group and died group. There were significant differences in maximum total bilirubin (Max-TB), maximum creatinine (Max-Cr), maximum WBC (Max-WBC) and minimum platelet count (Min-PL) between survived and died groups.
There were significant correlations between Max-TB and Max-Cr (r=0.491), Max-TB and Max-WBC (r=0.628), and Max-TB and Min PL (r=-0.646). The prognosis was poor in patients with 1) Max-TB more than 12.0 mg/dl, 2) Max-Cr more than 3.5 mg/dl, 3) Max-WBC more than 25000/mm3 and 4) Min-PL less than 5.0×104/mm3. All of the patients with factor 1) and another one out of 2), 3) and 4) were dead. Those would be valuable factors predicting the prognosis.
