Abstract
We experienced a case of multiple cancer in which rectal and gastric cancers developed after operations for heterochronous primary bilateral breast cancers.
The case involved a 51-year-old woman. The first cancer was detected in the right breast and a radical mastectomy was performed in March, 1984. In July, 1986, a modified radical mastectomy was performed for a left breast cancer, and the patient was diagnosed as having heterochronous primary bilateral breast cancers. After the second operation, there had been no sign of recurrence until February, 1994 when abdominal pain and anal bleeding appeared. With close examinations a diagnosis of synchronous double cancer of the rectum and stomach was made. Super low anterior resection of the rectum and subtotal gastrectomy were carried out on May 13. The rectum and subtotal gastrectomy were carried out on May 13. The postoperative course was uneventful and the patient was discharged from the hospital on July 4, 1994.
Except necropsy cases, multiple cancer of four organs has been reported in only 21 cases including this case in Japan so far. Among of them no such case involving bilateral breast cancers has been in the literature and there are few cases in which radical operation could be performed for all four lesions. We think that our case is so rare.
