2003 Volume 64 Issue 10 Pages 2410-2413
A 36-year-old woman was admitted to the hospital because of skin erythema and a tumor of the left breast. Clinical examinations showed highly suspicious inflammatory breast cancer. We performed a modified radical mastectomy after down stage due to neo-adjuvant chemotherapy. Histopathologically, it was diagnosed as comedo intraductal carcinoma at the whole gland without evidence of inflammatory breast cancer.
Inflammatory breast cancer has clinical characteristics of diffuse skin erythema, edema, and induration. Pathologically, it is diagnosed based on cancer cell embolism and invasion of cutaneous lymph vessel. While intraductal carcinoma rarely appears with inflammation at the skin, and so far only one case has been reported in Japan as far as we could review. We report this rare case of ductal carcinoma in situ presenting an appearance of inflammatory breast cancer, with a review of the literature.