Abstract
A 48-year-old woman was seen at the hospital because of a left breast mass. A 41×34mm demarcated tumor with smooth surface was present in the AC area of the left breast. No axillary lymph nodes were palpable. CT mammography showed an irregular tumor with ringed enhancement effect at the periphery. Fine needle aspiration biopsy resulted in ductal carcinoma with minute invasion. Left breast cancer (T2N0M0, StageIIA) was diagnosed and breast anserring surgery (Bp) and sentinel lymph node (SLN) biopsy were performed. SLN disclosed metastasis negative. Histopathological studies revealed invasive ductal carcinoma at the periphery and cartilaginous matrix with cancer cells at the center of the tumor. No spindle cells lay between cancer cells and cartilaginous matrix, and thus matrix-producing carcinoma (MPC) was diagnosed.
MPC is a subtype of breast cancers with osteocartilaginous metaplasia, and is an extremely rare entity. We present a review of the domestic cases of the disease as well as our case, making a special reference to the clinicopathological characteristics.