Abstract
Histological examinations of serial biopsies of bone marrow and autopsy materials were performed on cases of myeloid leukemia which had preleukemic state or atypical early manifestations.
Structural changes of bone marrow in so-called preleukemic state were classified in,
a. hypoplastic type
b. erythroproliferative type
c. granuloproliferative type
d. myeloproliferative type.
Characteristics of these types in their further course and autopsy findings were described. It was stressed, that myeloid leukemia with preleukemic state often showed also atypical autopsy findings, compared with myeloid leukemia without preleukemic state.
