Rinsho Ketsueki
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
Coagulation Study in Pancreatitis
Akio HIRAYAMASoichiro UEHARAYuji ITAGAKIShigeru IZUMIYAMAMamoru KUDOTatsuo SATO
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1974 Volume 15 Issue 2 Pages 171-176

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Abstract
We have examined blood coagulation and fibrinolytic activities in about 16 cases of pancreatitis and in 10 cases of normal adults.
In pancreatitis patients plasma fibrinogen level was elevated and P.T.T. shortened. In fibrinolytic system there is no remarkable change in systemic fibrinolytic activities, but EDP was remarkbly elevated in acute stage of pancreatitis.
In comparison beween arterial and venous blood, hypercoagulable state was observed with arterial blood more than with venous blood. And it was specific that Factor XII, XI and VIII in intrinsic coagulation system were elevated.
After injection of pancreozymin Secretin, the elevation of FDP, and decreasement of Fibrinogen and platelet aggregation were found.
From the results mentioned above, we concluded that in pancreatitis patients basic hypercoagulable state was found and at the acute stage intravascular coagulation will be occured.
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© 1974 The Japanese Society of Hematology
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