Abstract
Hyperfunction of the reticuloendothelial system (R. E. S.), lipid imbalance, autoimmune factor and others have been reported to cause hemolysis in chronic liver disorders.
According to the present results, the cause of hemolysis in the chronic liver disorders was partly due to the production of Malonyl-di-aldehyde (M. D. A.) and the lability of hexose monophosphate shunt (H. M. S.) in the erythrocyte membrane in addition to the above-mentioned mechanisms.
Our data revealed no relationship of hemolysis and plasma factors, such as serum cholesterol, albumin and γ-globulin.
By compensation of erythrocyte enzymodynamics of H. M. S., erythrocyte resistance in vitro increased and no relationship between M. D. A., G-6-P. D. and catalase was noted in the chronic liver disorders.
