Abstract
Nitroblue tetrazolium dye reduction test (NBT test) is used as one of the neutrophil function tests, especially for measurement of the ingestion and bactericidal potent of neutrophils.
Since the first report of Baehner & Nathan, this test has been employed for screening of chronic granulomatous diseases of infancy. But later, Park insisted that NBT test could be used for the differential diagnosis of non-bacterial infection from bacterial.
Thereafter this method was modified and simplified, but still remained some thechnical problems, which included the complexity of the test procedure and its inherent errors. In this paper Park's method was developed, using microcapillary tube to dissolve some of these problems.
Furthermore, it was confirmed that this test was valuable for differentiation of the bacterial and non-bacterial infections and for check of abnormalities of plasma factors, especially of complement-properdin systems.
