Abstract
A case of T cell chronic lymphocytic leukemia (CLL) associated with lung cancer found in a 33-year-old female was reported.
The proliferated leukemic cells in the peripheral blood were lymphocyte-like cells with smaller and lobulated or invaginated nuclei. The proliferated lymphocytes were identified as T cell by examing the surface markers. Spontaneous formation of rosettes with sheep erythrocytes (Erosettes) and cytotoxicity test with ATS were used as T cell markers whereas cytotoxicity test with ABS, receptor for the third component of complement (EAC-rosettes) and cell surface immunogloburin (Sm-Ig) were employed as B cell marker.
Such a case of CLL associated with malignant neoplasm is rare in Japan.