Abstract
A 26-year-old man. During the treatment on acute hepatitis, cystitis was complicated. After an administration of 5g of chloramphenicol and 8g of thiophenicol, he fell into pancytopenia and 16% of myeloblast was seen in the peripheral blood. However, no increase in myeloblasts was noted in the bone marrow. Anemia was improved when the drugs were discontinued, but thrombocytopenia persisted and a few myeloblasts were seen in the peripheral blood. He fell into severe anemia 6 months after the administration of chloramphenicol. He developed erythroleukemia with sideroblastic anemia. He became better for a moment after the administration of adrenocortical steroids, but he suffered from pneumonia at the end stage and died about 23 months after the occurrence of pancytopenia or 17 months after the occurrence of erythroleukemia. The authors reported this case with reference of the literature.
