Abstract
The characteristics of back-ground factors and hematological recovery patterns in 13 patients with fully remitted acquired aplastic anemia were analysed. Nine out of 13 patients were suggested to have somewhat etiologic factors: chloramphenicol, gold colloid, organic solvent or hepatitis. There were no remarkable differences in the age and sex between these patients and 92 control patients with aplastic anemia. The initial hematological damages in these 13 patients were estimated mild in 5, moderate in 7 and severe in 1.
The first signs of recovery in the hematological findings were noted from several months to one year, and remission was completed between 1 and 2 years after the onset of symptoms, and no reccurence of anemia has been observed until present time. The hematological recovery patterns showed no significant difference between the patients with or without androgen and/or crtico steroid therapy.
The high incidence of secondary cases and the similar recovering patterns of hematological findings in these 13 patients suggest that common pathogenesis and recovering mechanism may influence to this type of aplastic anemia, and that their hemopoietic recovery may be mainly resulted from their own hemopoietic abilities rather than therapeutic effect of the drugs.
