Abstract
A case of immunoblastic lymphadenopathy (IBL) with interstitial pneumonitis and pancytopenia was reported.
A 63-year-old male was admitted to our clinic with severe anemia and generalized lymphadenopathy. Laboratory findings were at follows: Hb 4.3 g/dl WBC 1,300/mm3, Platelets 4.9×104/mm3, Reticulocytes 0‰, CHA 1: 512, a positive Coombs test, hypocomplementemia and polyclonal hypergammaglobulinemia in immunoelectrophoresis. Biopsy specimen of the cervical lymph node showed diffuse proliferation of large lymphocytes (immunoblasts), abundunce of arbolizing small vessels and deposition of amorphous PAS-positive interstitial materials.
Although administration of prednisolone and blood transfusion resulted a partial remission, he died two months later.
Postmortem examination revealed hemosiderosis in liver and spleen, and a generalized fungal infection.
