1985 Volume 26 Issue 4 Pages 532-536
An autopsy case of macroglobulinemia with gastric cancer is reported. A 75-year-old woman was admitted because of edema and short of breath. At that time she had not lymphadenopathy and hepatosplenomegaly, but marked increase in serum monoclonal IgM of Kappa and 19S globulin were observed.
The patient was treated with melphalan and cyclophosphamide, but after six months she died bronchopneumonia.
At postmortem examination, a small nodule was found at the cardia that proved to be an advanced papillary adenocarcinoma. In recent years the reports of macroglobulinemia with malignant tumor are increasing in number in Japan.
