1988 Volume 29 Issue 11 Pages 2101-2104
Two cases of non-African Burkitt's lymphoma in long-term remission are reported. Case 1. A 52-year-old man developed incisional hernia after appendectomy and underwent re-operation in April, 1984, when he was noted to have an ileocecal tumor, 4 cm in diameter. Then, ileocecal resection was performed and he was histologically diagnosed as having Burkitt's lymphoma. He was given postoperative combination chemotherapy consisting of cyclophosphamide, adriamycin, vincristine and prednisolone (CHOP) and has been in complete remission for more than 40 months. Case 2. A 27-year-old woman was admitted to Nagasaki University Hospital with a rapidly growing tumor in the right breast at 24 weeks of pregnancy in October, 1982. Radical mastectomy and Cesarean section were performed. Histological examination of the tumor revealed that she had Burkitt's lymphoma. Cell marker study showed that the tumor cells were positive for IgM, κ type immunoglobulin. Then, combination chemotherapy of CHOP was stated. She has been in complete remission for more than 60 months after surgery. Extensive resection of tumor and intensive postoperative chemotherapy appear to be the treatment of choice in selective cases of Burkitt's lymphoma.