Rinsho Ketsueki
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
Malignant Lymphoma which Contained EBV DNA and Lacked EBNA2 Antibody
Misuzu SHIMAKAGE, Kanji HIRAI, Nobuko IKEGAMI, Toyoko MATSUBUCHI, Hiroya KAWAGOE
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Keywords: Epstein-Barr virus (EBV) DNA, EBV determined nuclear antigen 2 (EBNA2) antibody, malignant lymphoma
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1989 Volume 30 Issue 7 Pages 1091-1092

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Abstract

A case of non-Hodgkin malignant lymphoma which contained EBV DNA and EBNA was reported. The serum of this patient showed high titer of VCA, EA, and EBNA1 antibody but lacked EBNA2 antibody. The relation with EBV originated malignancy and defect of EBV specific antibody suggests a process of oncogenicity of this virus.

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© 1989 The Japanese Society of Clinical Hematology
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