Abstract
A 83-year-old woman, complaining of jaundice and anemia, was diagnosed as autoimmune hemolytic anemia (AIHA) with bilirubin gall stones. Her red blood cell (RBC) group was A, Rh (D)+, but the details were indefinite due to transfusions previously repeated, while anti-C3d serum reacted positively in the direct antiglobulin test. Her serum reacted with RBC other than R2R2 in the albumin (37°C) method and in the bromelin method, the reaction turning out negative after the pretreatment with 2ME.
These findings indicated the autoantibody was anti-e of IgM class, which had been so far rarely reported in Japan.
