2017 Volume 7 Issue 2 Pages 105-111
Nanotechnology is a leading tool for manufacturing highly functional drug formulations. The formulation techniques using nanotechnology include liposome, polymer nanoparticle, iron nanoparticle, nanoemulsion such as lipid microsphere, micelles, vaccine adjuvant, and nanocrystal technology. Some drug products using these techniques have been approved in Japan. Most of them have been used for the low-molecular-weight active substances. However, these techniques are recently used as the carriers for nucleic acids or proteins. Internationally, there has been a progress in nanomaterial measurement methods, development of reference materials, consensus-based documentary standards for nanotechnology. These activities are also important issues for us. Furthermore, we are involved in the development of new measurement methods for quality attributes which reflect the product performance of nanomedicines. We introduce our research to develop the evaluation method for bending modulus of liposomes using atomic force microscopy.
