Abstract
I had the honor of giving a plenary lecture entitled "Electrophoresis: Past, Present, and Future" for the 60th Anniversary of Japanese Electrophoresis Society (JES) in 2010. In this 62nd General Meeting of JES I had the honor of giving an educational lecture entitled "Trilogy of Electrophoresis" in which the short history of development of electrophoresis was started from the first report on phenomena of electrophoresis and electro-osmosis by Reuss in Russia. And the innovation of technology of moving boundary electrophoresis by Tiselius in Sweden for successful applications to separate serum proteins, especially the discovery of antibodies in gamma-fraction was awarded to Nobel prize in 1948. The development of Tiselius electrophoresis apparatus by Hirai and Shimao in Japan triggered the clinical applications for serum protein fractionation specific for diseases to establish JES in 1950 and the publication of a journal of Seibutsu-butsuri-kagaku. The promotion of electrophoresis techniques by JES also triggered the innovation of many types of electrophoresis successively using new support media in Japan. A unique electrophoresis technique was reported by Nakamura in Japan so called "Cross electrophoresis". The technique has been developed to be affinity electrophoresis which enabled us to separate proteins by bio-specific interactions with other proteins, nucleic acids, carbohydrates, and a wide-variety of substances. Those innovations of electrophoresis technique have much contributed to the development of bioscience and biotechnology in the world.
