Observation was made on 20 patients with various diseases who received the transplantation of cow's pituitary glands with regard to its therapeutical effect and the changes in the leucocyte and in the constituents of serum protein. Its therapeutical value differd from patient to patient depending upon the kind of disease. An appreciable effect was seen in Alopecia. As for the leucocyte counts, increase was noted in 8 cases, decrease in 6 cases, 4 of which had received the transplantation twice, and no mentionable changes in 9 cases.
A slight increase of the eosinophilic leucocyte was observed in 9 cases, a slight decrease in 5 cases and no changes in 3 cases.
An increase of gamma-globulin was seen in 4 cases, 10 cases showed no obvious changes and a slight decrease was detected in 9 cases.
From the results above mentioned, we were unable to draw any definite conclusion as to the effect of the transplantation of cow's pituitary glands upon the leucocyte and the constituents of serum protein.