Abstract
Enzyme activities and isozyme patterns of blood plasma were compared with those of heart muscles in the hypoxic states using Wistar male rats. The findings of myocardial damage during hypoxia were not so significant in plasma LDH-isozyme. Plasma LDH-isozyme did not show the pattern of heart muscles, but it was like that of the liver even in the hypoxic states. Pattern of plasma CK-isozyme during hypoxia resembled that of heart muscles except increasing CK-BB, and mitochondrial CK was also recognized in cathode side toward CK-MM in plasma. It could be said that hypoxia might play a important role as to the appearances of type 2 macro-CK in plasma. Plasma CK-isozyme indicated more quickly a findings of myocardial damage during hypoxia than plasma LDH-isozyme.
