接触皮膚炎と接触原調査 特に化粧品皮膚炎について

抄録

Patch test and photo-patch-test are carried out in patients with cosmetic dermatitis. The test results indicate that the untoward reactions to cosmetics are due predominantly to allergic sensitization rather than to primary irritation.
It is said that false negative reactions are common in testing with cosmetics, depending upon the test materials and test methods.
Five days or more after contact with the causative substance the sensitive states will develop. No sensitivity appears after repeated contact with cosmetics for many years in most individuals. Some may become sensitive after continual contact over a period of years.
The past history about the cosmetics has to be thoroughly inquired in patients with cosmetic dermatitis. All cosmetics that the patient has used must be taken into consideration. Cosmetics are used on the uncovered areas, so that photo-patch-test as well as patch-test must be carried out to determine the causatives. Thus, false negative reactions are avoidable.
A trial to determine the actual cause of sensitivity encounters the practical difficulties because of the industrial secret on cosmetic ingredients. Knowledge of the sensitizing ingredients of cosmetics is scanty.