Long Term Follow-up Study of “Moyamoya Disease” (Occlusion of Circle of Willis) with Drug Therapy

Abstract

Long term follow up study (3.5-16 years duration) was performed on 26 cases of Moyamoya disease with drug therapy. These cases were divided into two groups, using cerebral vasodilator and “cerebral vasodilator and metabolic activator”. There is no definite difference between two groups regarding clinical and EEG improvement when considered severity of the disease each cases.
Improvement of EEG in resting record and during and after hyperventilation with 5% CO₂ inhalation were obtained. All cases of former group revealed improvement of clinical symptoms, two fourth of later group showed clinical improvement as well.