Abstract
The epidemiological study on 100 cases with Moyamoya disease which have been experienced at Tohoku University from 1963 to 1980 is reported. Although the results of our study are not so different from those of ever reported epidemiological studies, high frequency of inflammation above the neck, especially recurrent chronic tonsillitis, in their past history was the different one. Namely, 74% of child and 46% of adult cases have experienced inflammations above the neck, i. e., chronic tonsillitis, otitis media and sinuitis maxillaris in their past history. Morbidity of this disease is high in young girl. The average age of the onset in children was 4 years and a half, and 35 years and a half in adults. The initial symptoms of children were those due to cerebral ischemia, such as paroxysmal hemiplegia, aphasia and mental handicap. On the contrary, in adults representative initial symptoms were those due to intracranial hemorrhage.
