Electrospinning is based on an electrohydrodynamic process, and it is a straightforward and versatile method for forming continuous thin fibers from several nanometers to several tens of micrometers in diameter. One major advantage of electrospinning is the one-step forming of nonwoven fibrous fabrics. In the present study, we prepared ultra-fine fiber nonwoven fabrics from 13 kinds of commercial polymers (e.g., PLA, PA, PU, Cellulose, PVDC, and PS) by electrospinning and tested their antimicrobial activity. Most of ultra-fine fiber nonwoven fabrics showed excellent antimicrobial activity. Our experimental results showed that there is close correlation between fiber diameter of nonwoven fabrics and their antimicrobial activity: the nonwoven fabrics with average fiber diameter of smaller than 800 nm showed better antimicrobial activity.
