Abstract
It is known that epileptic discharges on the electrocorticography, which cause seizures, are terminated by focal cooling of the cortical surface. In the previous study, the authors devised a focal cooling device with a thermoelectric chip and examined its performance to cool the cortex and to suppress the epileptic discharges through the animal studies. However, for the efficient development, it is needed to estimate the cooling performance through numerical simulations. Then the authors carry out a numerical simulations to analyze the heat conduction in the cortex when its surface is cooled by the thermoelectric chip. By comparing with the result of the animal study, the validity of the simulation is shown.