2025 Volume 77 Issue 2 Pages 123-126
To enhance drug permeation efficiency in drug delivery systems (DDS) for skin disease treatment, particulate microneedles, such as spicules, have gained attention. However, conventional materials face challenges, including potential adverse skin reactions and inconsistent needle shapes. This study aimed to fabricate an artificial spicule using magnesium (Mg), a biocompatible material that supports skin health maintenance. Electroplating was employed to precisely control the shape and dimensions of the Mg deposited within the predefined resist patterns. Consequently, Mg successfully deposited uniformly. Further research will focus on improving the fabrication stability to optimize the production of Mg artificial spicules for drug delivery.
