2017 Volume 30 Issue 6 Pages 365-372
An analytical method for chloric acid in drinking water was examined using liquid chromatography-tandem mass spectrometry (LC/MS/MS). As an analytical method, the sample was diluted to 100 times (V/V) with purified water and subjected to LC/MS/MS measurement. This analysis indicated that the calibration curve of chloric acid showed good linearity in the range of 0.2–10 µg/L (sample concentration: 20–1000 µg/L) while the repeatability of results. The repeatability accuracy (RSD) of measurement of 0.5 µg/L chloric acid standard solution (n＝5) was as good as 4.56％. In addition, the repeatability (8.99％), intermediate precision (9.47％), accuracy (105％) for determining chloric acid in drinking water, as obtained by recovery tests in (50 µg/L : n＝5 : 5 days) , satisfied with the criteria in the guidelines for the validation of the testing method for drinking water, as established by the Ministry of Health, Labour and Welfare, Japan. Furthermore, it was confirmed that this analytical method can selectively detect chloric acid in drinking water, which can not be determined via ion chromatography.
