2004 Volume 52 Issue 3 Pages 171-179
For empiric therapy against infections, it is most important to select antibiotics on the basis of statistical analyses of drug-resistance of the bacteria isolated in a hospital or a region. In this study, we examined the drug-resistance of Acinetobacter species (A. baumannii, A. lwoffi, and other Acinetobacter species) and Stenotrophomonas maltophilia (S. maltophilia) isolated at Shinshu University Hospital from October 2000 to December 2003. Acinetobacter species and S. maltophilia are becoming important as nosocomial opportunistic pathogens as well as Pseudomonas aeruginosa. Most strains of Acinetobacter species were susceptible to piperacillin, 3rd generation cephalosporines, carbapenems, aminoglycosides and quinolones ; some strains of A. baumannii, however, showed multi-drug resistance, especially to carbapenems. On the other hand, S. maltophilia were resistant to most antibiotics except minocycline, sulfamethoxazole-trimethoprim and levofloxacin.
