2007 Volume 28 Issue 1 Pages 18-23
We evaluated the usefulness of intravenous antimicrobial therapy for the treatment of infantile intractable recurrent middle otitis in the outpatient department, and obtained the following results:
1. Continuous intravenous therapy with 60 mg/kg/day ceftriaxone (CTRX) in the outpatient department resolved infantile intractable recurrent middle otitis in all patients in a 3-day period. This result was obtained even though previously, a combination of an indwelling tympanic ventilation tube and oral administration of antimicrobial drugs had been ineffective in these patients.
2. This intravenous antimicrobial therapy in the outpatient department was considered useful for the treatment of infantile intractable recurrent middle otitis.
3. However, since CTRX administration to children once per day is not an approved indication, it is necessary to evaluate its usefulness in a large population to expand the indications.
4. Since continuous 3day intravenous therapy in the outpatient department is often difficult for otorhinolaryngologists to perform in infants in whom intractable recurrent middle otitis is common, close cooperation with pediatricians is important.