Abstract
Kawasaki disease is well known as an acute systematic inflammatory disease, which typically occurs in children at an age of ≤10 years. Numerous common head and neck manifestations are reported; however, retropharyngeal abscess is extremely rare. We reported two cases of Kawasaki disease with retropharyngeal abscess. Both cases (5-year old boy and 4-year old girl) showed cervical lymph node swelling, high fever, and retropharyngeal antibiotics-resistant abscess. Though no surgical intervention was performed for the retropharyngeal abscess, all the symptoms subsided after the administration of intravenous immunoglobulin and aspirin. When physicians encounter a case of antibiotics-resistant retropharyngeal abscess, they should rule out Kawasaki disease.