Abstract
Chronic mucocutaneous candidiasis is a primary immune deficiency syndromes, characterized by recurrent superficial Candida infection. We described a 1-year-old boy, who had recurrent stomatitis. His stomatitis did not improve with the orally administered anti-fungal drug, Amphotericin-B, so he was admitted to the hospital for treatment with the intravenous anti-fungal drug Micafungin sodium. Immunological examinations revealed positive lymphocyte stimulation test results using Candida antigen without delayed-type hypersensitivity reaction to Candida. The lgG2 subclass titer was below the lower limit of the normal range. Although he was managed by regular use of Amphotericin-B for prophylaxis, he had recurrence of stomatitis, and administration of the oral systemic antifungal drug, Fluconazole, was needed.
