高インピーダンス神経電極用多チャンネル電流刺激チップの開発

抄録

We developed a prototype of a multi-channel current stimulator chip that can be connected to high-impedance neural stimulating electrodes was designed and fabricated by utilizing 0.25µm high-voltage CMOS technology. The chip consists of five current buffers for the line-parallel multi-channel outputs and multiple registers for setting the stimulation parameters, enabling a multiplexed stimulation with up to 20 channels per chip. The current buffer was designed to generate biphasic pulses with the maximum amplitude of ±100µA. We demonstrated that the current pulses generated by our chip were able to be delivered to the mammalian brain in-vivo.