2014 Volume 50 Issue 8 Pages 602-607
We investigated the relationship between the green auto-fluorescence (GAF) and the spontaneous electro-encephalographic signals (EEG) recorded from the neocortex of mice under urethane anesthesia. Power spectral density analysis showed that both the GAF and the EEG have a significant activity in the delta frequency band (0.5-1Hz). Cross-correlation analysis and coherence analysis revealed that the GAF and the EEG were correlated in the delta frequency band. These results suggest that the delta frequency component of GAF would be useful to study the spontaneous activity of the neocortex. Visualization of the spatio-temporal dynamics of the GAF delta activity revealed complex phenomena such as propagation of the localized activity and disappearance of the activity after collision. These data suggest the usability of GAF for investigation of the delta activity.